Acquired hemophilia and its treatment.

摘要: The development of auto-antibodies against clotting factor VIII is a rare disease that occurs predominantly in adults: pregnant women or people with various immunologic disorders no apparent underlying disease. As consequence an immune system dysregulation, the evolution this condition unpredictable. aim treatment to restore normal levels circulation using desmopressin (DDAVP), massive doses (human porcine), plasmapheresis and infusions. In patients high-titer inhibitors, products 'bypasing' activity can be used. most difficult task treat disorder. High-dose infusions immunoglobulins might useful, due presence anti-idiotypes inhibitors commercial preparations. Corticosteroids cyclophosphamide are currently widely used treatments for