A 24-h energy expenditure study on reduced-obese and nonobese women: effect of beta-blockade.

作者: B Buemann , A Astrup , J Madsen , N J Christensen

DOI: 10.1093/AJCN/56.4.662

关键词: Carbohydrate metabolismChemistryFatty acidPropranololC-peptideBlood plasmaBlood sugarInternal medicineInsulinLipid oxidationEndocrinology

摘要: Twenty-four-hour energy expenditure (EE) and substrate oxidation rates were studied in a respiration chamber 15 reduced-obese (BMI = 24.7) 8 nonobese 20.1) women. Two experiments performed, one which beta-blockade was introduced by propranolol with placebo. When adjusted for differences fat-free mass, no difference 24-h EE found between the groups placebo experiments. Propranolol reduced 2.7% group whereas reduction seen group. A positive correlation fasting glycerol concentration lipid oxidation. During daytime, carbohydrate increased only subjects. free fatty acid concentrations both groups. Beta-blockade seems to have little effect on sedentary but may suppressing combustion.

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