Noncontact fluorescence diffuse optical tomography of heterogeneous media

作者: L. Hervé , A. Koenig , A. Da Silva , M. Berger , J. Boutet

DOI: 10.1364/AO.46.004896

关键词: Light propagationComputed tomographyFluorescenceComputer scienceSmall animalOpticsTissue heterogeneityDiffuse optical imaging

摘要: Fluorescence-enhanced diffuse optical tomography is expected to be useful the collection of functional information from small animal models. This technique currently limited by extent tissue heterogeneity and management shape animals. We propose an approach based on reconstruction object heterogeneity, which provides original solution two problems. Three evaluation campaigns are described: first were performed phantoms designed test reconstructions in highly heterogeneous media noncontact geometries; third was conducted mice with lung tumors fluorescence yield feasibility vivo.

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