作者: L. Hervé , A. Koenig , A. Da Silva , M. Berger , J. Boutet
DOI: 10.1364/AO.46.004896
关键词: Light propagation 、 Computed tomography 、 Fluorescence 、 Computer science 、 Small animal 、 Optics 、 Tissue heterogeneity 、 Diffuse optical imaging
摘要: Fluorescence-enhanced diffuse optical tomography is expected to be useful the collection of functional information from small animal models. This technique currently limited by extent tissue heterogeneity and management shape animals. We propose an approach based on reconstruction object heterogeneity, which provides original solution two problems. Three evaluation campaigns are described: first were performed phantoms designed test reconstructions in highly heterogeneous media noncontact geometries; third was conducted mice with lung tumors fluorescence yield feasibility vivo.