Soluble Epoxide Hydrolase Inhibition and Epoxyeicosatrienoic Acid Treatment Improve Vascularization of Engineered Skin Substitutes
作者： Dorothy M. Supp , Jennifer M. Hahn , Kevin L. McFarland , Kelly A. Combs , Kin Sing Stephen Lee
DOI: 10.1097/GOX.0000000000001151
关键词: Vascular plexus 、 Medicine 、 Epoxyeicosatrienoic acid 、 Skin substitutes 、 Grafting 、 Epoxide hydrolase 2 、 Adjunctive treatment 、 Biochemistry
摘要: Background:Autologous engineered skin substitutes comprised of keratinocytes, fibroblasts, and biopolymers can serve as an adjunctive treatment for excised burns. However, lacks a vascular plexus at the time grafting, leading to slower vascularization reduced rates engraftm
sci-hub.se 参考文章(36)
Annika I. Ostermann, Jan Herbers, Ina Willenberg, Rongjun Chen, Sung Hee Hwang, Robert Greite, Christophe Morisseau, Faikah Gueler, Bruce D. Hammock, Nils Helge Schebb, Oral treatment of rodents with soluble epoxide hydrolase inhibitor 1-(1-propanoylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea (TPPU): Resulting drug levels and modulation of oxylipin pattern Prostaglandins & Other Lipid Mediators. ,vol. 121, pp. 131- 137 ,(2015) , 10.1016/J.PROSTAGLANDINS.2015.06.005
Lavinia Tran, Andrew R. Kompa, Bing H. Wang, Henry Krum, Evaluation of the effects of urotensin II and soluble epoxide hydrolase inhibitor on skin microvessel tone in healthy controls and heart failure patients. Cardiovascular Therapeutics. ,vol. 30, pp. 295- 300 ,(2012) , 10.1111/J.1755-5922.2011.00282.X
Yong Zhou, Guo-Ying Sun, Tian Liu, Jia-Xi Duan, Hui-Fang Zhou, Kin Sing Lee, Bruce D. Hammock, Xiang Fang, Jian-Xin Jiang, Cha-Xiang Guan, Soluble epoxide hydrolase inhibitor 1-trifluoromethoxyphenyl-3- (1-propionylpiperidin-4-yl) urea attenuates bleomycin-induced pulmonary fibrosis in mice Cell and Tissue Research. ,vol. 363, pp. 399- 409 ,(2016) , 10.1007/S00441-015-2262-0
Bora Inceoglu, Ahmed Bettaieb, Carlos A. Trindade da Silva, Kin Sing Stephen Lee, Fawaz G. Haj, Bruce D. Hammock, Endoplasmic reticulum stress in the peripheral nervous system is a significant driver of neuropathic pain Proceedings of the National Academy of Sciences. ,vol. 112, pp. 9082- 9087 ,(2015) , 10.1073/PNAS.1510137112
Arzu Ulu, Kin Sing Stephen Lee, Christina Miyabe, Jun Yang, Bruce G. Hammock, Hua Dong, Bruce D. Hammock, An omega-3 epoxide of docosahexaenoic acid lowers blood pressure in angiotensin-II-dependent hypertension. Journal of Cardiovascular Pharmacology. ,vol. 64, pp. 87- 99 ,(2014) , 10.1097/FJC.0000000000000094
Yan Wang, Xin Wei, Xiao Xiao, Rutai Hui, Jeffrey W. Card, Michelle A. Carey, Dao Wen Wang, Darryl C. Zeldin, Arachidonic Acid Epoxygenase Metabolites Stimulate Endothelial Cell Growth and Angiogenesis via Mitogen-Activated Protein Kinase and Phosphatidylinositol 3-Kinase/Akt Signaling Pathways Journal of Pharmacology and Experimental Therapeutics. ,vol. 314, pp. 522- 532 ,(2005) , 10.1124/JPET.105.083477
M.W. Laschke, M.D. Menger, Vascularization in tissue engineering: angiogenesis versus inosculation. European Surgical Research. ,vol. 48, pp. 85- 92 ,(2012) , 10.1159/000336876
B. Inceoglu, S. L. Jinks, A. Ulu, C. M. Hegedus, K. Georgi, K. R. Schmelzer, K. Wagner, P. D. Jones, C. Morisseau, B. D. Hammock, Soluble epoxide hydrolase and epoxyeicosatrienoic acids modulate two distinct analgesic pathways. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 105, pp. 18901- 18906 ,(2008) , 10.1073/PNAS.0809765105
Steven T. Boyce, Richard J. Kagan, Kevin P. Yakuboff, Nicholas A. Meyer, Mary T. Rieman, David G. Greenhalgh, Glenn D. Warden, Cultured Skin Substitutes Reduce Donor Skin Harvesting for Closure of Excised, Full-Thickness Burns Annals of Surgery. ,vol. 235, pp. 269- 279 ,(2002) , 10.1097/00000658-200202000-00016
Ambra Pozzi, Ines Macias-Perez, Tristin Abair, Shouzuo Wei, Yan Su, Roy Zent, John R. Falck, Jorge H. Capdevila, Characterization of 5,6- and 8,9-Epoxyeicosatrienoic Acids (5,6- and 8,9-EET) as Potent in Vivo Angiogenic Lipids Journal of Biological Chemistry. ,vol. 280, pp. 27138- 27146 ,(2005) , 10.1074/JBC.M501730200