Surface-selective and controllable photo-grafting for synthesis of tailored macroporous membrane adsorbers

摘要: Photo-grafting is a straightforward and promising technique for surface modification of polymeric membranes. This work emphasized on the development investigation surface-selective photo-grafting method from polar organic solution; other hand, preparation membrane adsorbers via proposed grafting methods evaluation resulting adsorbers. Two novel have been developed: synergist immobilization iniferter methods. Hydrophilized polypropylene (PP) microfiltration (MF) membrane, whose polymer layer contains polyacrylate, was used as base both methods; track-etched polyethylene terephthalate (PET) MF membranes (PET200 PET400) were extension further investigation; methanol or acetonitrile solution acrylamide (AAm) with/without cross-linker (EDMA) applied mechanism. For method, (tertiary amino groups) photo-initiator benzophenone (BP) introduced onto an aminolysis reaction with diethyl ethylenediamine (DEEDA). The conditions optimized. mechanism verified by significant difference in degree (DG) between original aminolysed In order to better understand improve this detailed functionalization parameters affecting factors has carried out. grafted characterized ATR-IR, contact angle, SEM, permporometry, liquid permeability zeta potential. obtained results demonstrated that highest surface-selectivity could be achieved only under optimum conditions, i.e., inert solvent excited BP should reduce/avoid homopolymerization bulk appropriately low UV intensity exclude uncontrolled side (another discovered at high based direct generation starter radical); concentration reduce non-selective photo-grafting. Thus, well controlled immobilized concentration, irradiation time, monomer initiator concentration. addition, successfully PET it also expected functionalize similar chemical structure. For photo-iniferter (dithiocarbamate group) relationship DG Detailed respect efficiency, uniformity whole structure exhibited uniform controllability. However, re-initiation efficiency selected system value continuous intermittent irradiation. Via developed conventional adsorption three types anion-exchange (low density slightly cross-linked layer) prepared aqueous (2-(methacryloyloxy)ethyl) trimethylammonium chloride (MAETMAC) EDMA, using hydrophilized PP support. effect architecture protein binding capacity investigated. Buffer/elution permeability, static dynamic behaviors determined Analyses cross-linking can adsorbers. But relatively membrane. comparison, improved overall performance. compared more efficient suitable three-dimensional higher performance method. For affinity PET400 special functional copolymer bisphosphonate ester groups solution. showed proteins. Especially, found markedly lysozyme than cytochrome C, proteins pI size. With separation realized 1:1 mixture C very selectivity. Using MIP thin-layer composite immobilization. imprinting not observed probably due influence stability formed complex template optimization composition performed. Iniferter would alternative. synthesized but still progress.