Fatty Acid Synthesis in Human Adipose Tissue

摘要: The concentration of enzymes required for fatty acid synthesis was considerably less in extracts prepared from human omental adipose tissue than rat epididymal fat. Overall rates as measured by the incorporation radioactive precursors into acids were also much lower tissue. most striking difference found with citrate-1,5-14C, incorporating compound at a rate one-tenth that This finding consistent virtual absence citrate cleavage enzyme By contrast, activities pyruvate carboxylase and phosphoenolpyruvate carboxykinase, two necessary glyceride glycerol pyruvate, long chain activating (or enzymes) essentially similar both tissues. results are hypothesis de novo is not an important physiological function