Protists and the Wild, Wild West of Gene Expression: New Frontiers, Lawlessness, and Misfits.

作者: David Roy Smith , Patrick J. Keeling

DOI: 10.1146/ANNUREV-MICRO-102215-095448

关键词: Trans-splicingRegulation of gene expressionGeneticsSimplicityProtistExpression (architecture)Gene expressionRNA editingBiologyEvolutionary biologyGenome

摘要: The DNA double helix has been called one of life's most elegant structures, largely because its universality, simplicity, and symmetry. expression information encoded within DNA, however, can be far from simple or symmetric is sometimes surprisingly variable, convoluted, wantonly inefficient. Although exceptions to the rules exist in certain model systems, true extent which life stretched limits gene made clear by nonmodel particularly protists (microbial eukaryotes). nuclear organelle genomes are subject tangled forms yet identified. complicated extravagant picture underlying genetics eukaryotic microbial changes how we think about flow genetic evolutionary processes shaping it. Here, discuss origins, diversity, growing interest noncanonical protist relationship genomic architecture.

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