In vitro susceptibility of Helicobacter pylori to protolichesterinic acid from the lichen Cetraria islandica.
作者： K Ingolfsdottir , M A Hjalmarsdottir , A Sigurdsson , G A Gudjonsdottir , A Brynjolfsdottir
DOI: 10.1128/AAC.41.1.215
关键词: Antibacterial agent 、 Helicobacter pylori 、 Cetraria 、 Pharmacognosy 、 Bacteria 、 Iceland moss 、 Biology 、 Biological activity 、 Spirillaceae 、 Microbiology
摘要: With reference to the traditional use of Cetraria islandica (Iceland moss) for relief gastric and duodenal ulcer, plant extracts were screened in vitro activity against Helicobacter pylori. (+)-Protolichesterinic acid, an aliphatic alpha-methylene-gamma-lactone, was identified as active component. The MIC range protolichesterinic free well salt form, 16 64 micrograms/ml.
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