Use of emt gene signatures in cancer drug discovery, diagnostics, and treatment
作者： Gretchen M. Argast , Stuart Thomson , Joerg Heyer , Murray Robinson , Matthew E. O'connor
DOI:
关键词: Tumor cells 、 Bioinformatics 、 Gene 、 Biology 、 Gene signature 、 Cancer drug discovery 、 Cancer 、 Diagnostic methods 、 Kinase 、 Cancer research 、 Index score
摘要: The present invention provides diagnostic methods for assessing the EMT status of tumor cells, and predicting effectiveness treatment a cancer patient with an EGFR or IGF-1R kinase inhibitor, utilizing gene signature index score. further treating patients that incorporate these methods.
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