Impact of Proinflammatory Cytokines on Adipocyte Insulin Signaling

作者: Jean-François Tanti , Jennifer Jager , Yannick Le Marchand-Brustel

DOI: 10.1007/978-2-8178-0343-2_21

关键词: Adipose tissueType 2 diabetesInsulin resistantMedicineObesityInsulin resistanceProinflammatory cytokineAdipocyteInsulin receptorImmunology

摘要: Obesity is associated with a chronic low-grade inflammatory state. Inflammatory cytokines that are produced in adipose tissue during obesity involved the development of an insulin resistant state and they participate type 2 diabetes other metabolic complications obesity. In this chapter, we will describe network signaling proteins which used by to decrease action. We discuss possibility inhibit as new avenues for treatment resistance

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