Epidemiology of Motor-Neuron Diseases
作者： A. Roger Bobowick , Jacob A. Brody
DOI: 10.1056/NEJM197305172882005
关键词: Progressive muscular atrophy 、 Amyotrophic lateral sclerosis 、 Disease 、 Motor neuron 、 Pathology 、 Progressive bulbar palsy 、 Epidemiology 、 Medicine 、 General Medicine
摘要: THE motor-neuron diseases as considered here include the clinical syndromes that have been shown to be due primary abnormalities of anterior-horn cells and motor cranial-nerve nuclei. The term disease is used in a more restricted sense for syndrome amyotrophic lateral sclerosis components, progressive muscular atrophy bulbar palsy. Although these disorders similar pathologic substrate expression, they do not necessarily share same causal factors. Some are clearly hereditary, sporadic 95 per cent cases. In recent years, distinctions between major . . .
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