A Facile Synthesis of 3,4-Diamino-2,5-Diacylthieno[2,3-b]Thiophenes from Disodium(Dimercaptomethylene)Malononitrile and α-Halo Ketones
作者： Toshio Fuchigami , Zaghloul El-Shahat Kandeel , Tsutomu Nonaka , Hsien-Ju Tien
关键词: Intramolecular cyclization 、 Sydnone 、 Polymer chemistry 、 Malononitrile 、 Chemistry 、 Derivative (chemistry)
摘要: Various kinds of α-halo ketones readily reacted with disodium (dimercaptomethylene)malononitrile to give the corresponding 34-diamino-2,5-diacylthieno-[2,3-b]thiophenes in good excellent yields. The reaction was successfully extended synthesis a thienothiophene derivative having two sydnone rings by using 4-(bromoacetyl)sydnone.
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