Combination compositions containing benazepril or benazeprilat and valsartan

作者: Randy Lee Webb , David Saul Cohen , Marc De Gasparo

DOI:

关键词: ValsartanBenazeprilatBenazeprilMedicinePharmacologyHeart failure

摘要: The invention relates to pharmaceutical combination compositions for the treatment of hypertension, congestive heart failure and renal failure, comprising (1) ACE-inhibitor benazepril formula (I) or benazeprilat (II) a pharmaceutically acceptable salt thereof, (2) AT1-antagonist valsartan (III) as weel methods failure.

参考文章(3)
Olivier Madonna, Bernard Lacour, Francois Schmitt, Thierry Hannedouche, Combination of angiotensin converting enzyme inhibitors and aii antagonists ,(1993)
Michelle K. Bazil, Randy L. Webb, Hemodynamic effects of amlodipine and benazeprilat in spontaneously hypertensive rats. Journal of Cardiovascular Pharmacology. ,vol. 21, pp. 405- 411 ,(1993) , 10.1097/00005344-199303000-00009