Serine phosphorylation of STATs
作者： Thomas Decker , Pavel Kovarik
关键词: Phosphorylation 、 Serine 、 Biology 、 Biochemistry 、 Signal transduction 、 Tyrosine phosphorylation 、 Protein phosphorylation 、 Protein kinase A 、 Kinase 、 Phosphorylation cascade 、 Genetics 、 Cancer research 、 Molecular biology
摘要: … a C-terminal tyrosine residue which becomes phosphorylated in … It appeared initially that a single STAT tyrosine residue is all … found phosphorylated also on serine residues in a stimulus-…
nature.com
sci-hub.se 参考文章(69)
M. Müller, C. Laxton, J. Briscoe, C. Schindler, T. Improta, J.E. Darnell, G.R. Stark, I.M. Kerr, Complementation of a mutant cell line : central role of the 91 kDa polypeptide of ISGF3 in the interferon-alpha and -gamma signal transduction pathways The EMBO Journal. ,vol. 12, pp. 4221- 4228 ,(1993) , 10.1002/J.1460-2075.1993.TB06106.X
C. Beadling, J. Ng, J. W. Babbage, D. A. Cantrell, Interleukin-2 activation of STAT5 requires the convergent action of tyrosine kinases and a serine/threonine kinase pathway distinct from the Raf1/ERK2 MAP kinase pathway The EMBO Journal. ,vol. 15, pp. 1902- 1913 ,(1996) , 10.1002/J.1460-2075.1996.TB00541.X
Eric Caldenhoven, Thamar B. van Dijk, Roberto Solari, John Armstrong, Jan A. M. Raaijmakers, Jan-Willem J. Lammers, Leo Koenderman, Rolf P. de Groot, STAT3β, a Splice Variant of Transcription Factor STAT3, Is a Dominant Negative Regulator of Transcription Journal of Biological Chemistry. ,vol. 271, pp. 13221- 13227 ,(1996) , 10.1074/JBC.271.22.13221
F.A. Gonzalez, D.L. Raden, R.J. Davis, Identification of substrate recognition determinants for human ERK1 and ERK2 protein kinases. Journal of Biological Chemistry. ,vol. 266, pp. 22159- 22163 ,(1991) , 10.1016/S0021-9258(18)54548-8
I. Clark-Lewis, J.S. Sanghera, S.L. Pelech, Definition of a consensus sequence for peptide substrate recognition by p44mpk, the meiosis-activated myelin basic protein kinase. Journal of Biological Chemistry. ,vol. 266, pp. 15180- 15184 ,(1991) , 10.1016/S0021-9258(18)98601-1
A Eilers, D Georgellis, B Klose, C Schindler, A Ziemiecki, A G Harpur, A F Wilks, T Decker, Differentiation-regulated serine phosphorylation of STAT1 promotes GAF activation in macrophages. Molecular and Cellular Biology. ,vol. 15, pp. 3579- 3586 ,(1995) , 10.1128/MCB.15.7.3579
Robert A. Kirken, M. Grazia Malabarba, Jun Xu, Xiuwen Liu, William L. Farrar, Lothar Hennighausen, Andrew C. Larner, Philip M. Grimley, Hallgeir Rui, PROLACTIN STIMULATES SERINE/TYROSINE PHOSPHORYLATION AND FORMATION OF HETEROCOMPLEXES OF MULTIPLE STAT5 ISOFORMS IN NB2 LYMPHOCYTES Journal of Biological Chemistry. ,vol. 272, pp. 14098- 14103 ,(1997) , 10.1074/JBC.272.22.14098
Johannes G. Bode, Petros Gatsios, Stephan Ludwig, Ulf R. Rapp, Dieter Häussinger, Peter C. Heinrich, Lutz Graeve, The Mitogen-activated Protein (MAP) Kinase p38 and Its Upstream Activator MAP Kinase Kinase 6 Are Involved in the Activation of Signal Transducer and Activator of Transcription by Hyperosmolarity Journal of Biological Chemistry. ,vol. 274, pp. 30222- 30227 ,(1999) , 10.1074/JBC.274.42.30222
Cheh Peng Lim, Xinmin Cao, Serine Phosphorylation and Negative Regulation of Stat3 by JNK Journal of Biological Chemistry. ,vol. 274, pp. 31055- 31061 ,(1999) , 10.1074/JBC.274.43.31055
T. G. Boulton, Z. Zhong, Z. Wen, J. E. Darnell, N. Stahl, G. D. Yancopoulos, STAT3 activation by cytokines utilizing gp130 and related transducers involves a secondary modification requiring an H7-sensitive kinase Proceedings of the National Academy of Sciences of the United States of America. ,vol. 92, pp. 6915- 6919 ,(1995) , 10.1073/PNAS.92.15.6915