Drug-food interactions in clinical practice

摘要: Drug-food interactions are a significant problem in clinical practice. Foods may alter the effects of drugs by interfering with pharmacokinetic processes, such as absorption and elimination. For example, tetracyclines is decreased when taken milk or other dairy products. Pharmacologic pharmacodynamic mechanisms also play an important role drug-food altering drug effects. An example interaction warfarin sodium leafy green vegetables, whereby hypoprothrombinemic effect be thromboembolic complications develop. Similarly, certain have on food intake, absorption, metabolism, utilization. Numerous drugs, antineoplastic agents, been shown to suppress appetite, resulting intake nutritional deficiency. It that health care providers, physicians, pharmacists, dietitians, recognize work team prevent interactions. Minimizing adverse would improve patient optimizing therapeutic maintaining proper status.