In vitro performance of ceramic coatings obtained by high velocity oxy-fuel spray

作者: H. Melero , N. Garcia-Giralt , J. Fernández , A. Díez-Pérez , J.M. Guilemany

DOI: 10.3233/BME-140989

关键词: CeramicCoatingViability assayMaterials scienceHigh velocityPolystyreneIn vitroOxy-fuelThermal sprayingChemical engineering

摘要: Hydroxyapatite coatings obtained by plasma-spraying have been used for many years to improve biological perfor- mance of bone implants, but several studies drawn attention the problems arising from high temperatures and lack mechanical properties. In this study, is substituted velocity oxy-fuel (HVOF) spray, with lower reached, TiO2 added in low amounts hydroxyapatite order Four conditions tested evaluate which are those better Viability proliferation tests, as well differentiation assays morphology observation, performed human osteoblast cultures onto studied coatings. The hydroxyapatite-TiO2 maintain good cell viability proliferation, especially cases higher amorphous phase amount specific surface, promote excellent differentiation, a ALP these than polystyrene controls. Observation SEM corroborates behaviour. conclusion, alternative industrially, an interesting issue would be improving behaviour worst cases, turn show

参考文章(26)
Wei Gao, Mohammad Mohsin Hossain, How is the Surface Treatments Influence on the Roughness of Biocompatibility Trends in biomaterials & artificial organs. ,vol. 22, ,(2009)
P. A. Ramires, F. Cosentino, E. Milella, P. Torricelli, G. Giavaresi, R. Giardino, In vitro response of primary rat osteoblasts to titania/hydroxyapatite coatings compared with transformed human osteoblast-like cells Journal of Materials Science: Materials in Medicine. ,vol. 13, pp. 797- 801 ,(2002) , 10.1023/A:1016183326864
M.F. Morks, Fabrication and characterization of plasma-sprayed HA / SiO2 coatings for biomedical application Journal of The Mechanical Behavior of Biomedical Materials. ,vol. 1, pp. 105- 111 ,(2008) , 10.1016/J.JMBBM.2007.04.003
E. Charrière, S. Terrazzoni, C. Pittet, Ph. Mordasini, M. Dutoit, J. Lemaı̂tre, Ph. Zysset, Mechanical characterization of brushite and hydroxyapatite cements. Biomaterials. ,vol. 22, pp. 2937- 2945 ,(2001) , 10.1016/S0142-9612(01)00041-2
H. Melero, J. Fernández, S. Dosta, J. M. Guilemany, Caracterización de nuevos recubrimientos biocompatibles de hidroxiapatita-TiO 2 obtenidos mediante Proyección Térmica de Alta Velocidad Boletin De La Sociedad Espanola De Ceramica Y Vidrio. ,vol. 50, pp. 59- 64 ,(2011) , 10.3989/CYV.082011
Akiyoshi Osaka, Jin-Ming Wu, Satoshi Hayakawa, Kanji Tsuru, Low‐Temperature Preparation of Anatase and Rutile Layers on Titanium Substrates and Their Ability To Induce in Vitro Apatite Deposition Journal of the American Ceramic Society. ,vol. 87, pp. 1635- 1642 ,(2004) , 10.1111/J.1551-2916.2004.01635.X
John P. Collier, Victor A. Surprenant, Michael B. Mayor, Marguerite Wrona, Robert E. Jensen, Helene P. Surprenant, Loss of hydroxyapatite coating on retrieved, total hip components. Journal of Arthroplasty. ,vol. 8, pp. 389- 393 ,(1993) , 10.1016/S0883-5403(06)80037-9