Immunotoxic and hematotoxic effects of occupational exposures.

摘要: The toxic effects of environmental factors at work places on the hematopoietic and immune systems are basic importance due to time exposure, lasting average 8 hours daily during one week. Porphyrinurias porphyrias have been observed after exposure hexachlorobenzene, chlorinated dibenzodioxins, polychlorinated biphenyls, polybrominated vinyl chloride lead. Aplastic anemia may occur benzene, pesticides, arsenic, cadmium copper compounds. Megaloblastic has noted in subjects exposed chlordane, benzene nitrous oxide. Methemoglobinemia is induced by aromatic nitro amino Hemolytic reactions caused methyl chloride, naphthalene, lead, mercury compounds represent a separate problem. Immunodeficiencies resulting decreased antitumor antiinfectious immunity reported asbestos, ozone, dimethylsulphoxide, vinilidene homologues. Lymphocytopenia be manganese, toluene industrial noise. Neutropenia was marked carbon disulphide, arsenic compounds, electromagnetic fields. Only few reports concern lymphocyte T3, T4 T8 subpopulations. Electromagnetic fields (microwaves) cause an imbalance that subpopulation, consisting decrease cell count. neutrophil enzymes, such as myeloperoxidase alkaline phosphatase, their activity chlorobenzene DDT. A majority agents cited include genotoxic reflected chromosome aberrations increased sister chromatid exchange abnormal unscheduled DNA synthesis. Leukemia or lymphoma risk fields, irradiation.