Cranberries for treating urinary tract infections.

作者: Ruth G Jepson , Lara Mihaljevic , Jonathan C Craig

DOI: 10.1002/14651858.CD001322

关键词: PlaceboAlternative medicineCRANBERRY JUICEMedicineEnglish languageDouble blindMEDLINEUrinary systemSurgeryInternal medicine

摘要: Background Cranberries (particularly in the form of cranberry juice) have been used widely for several decades prevention and treatment urinary tract infections. The aim this review is to assess effectiveness cranberries treating such Objectives To Search strategy search developed by Cochrane Renal Group was used. Also, companies involved with promotion distribution preparations were contacted; electronic databases Internet searched using English non language terms; reference lists articles relevant trials also searched. Selection criteria All randomised or quasi controlled juice products Trials men, women children included. Data collection analysis Titles abstracts studies that potentially screened one reviewer, RJ, who discarded clearly ineligible but aimed be overly inclusive rather than risk losing studies. Reviewers RJ LM independently assessed whether met inclusion criteria. Further information sought from authors where papers contained insufficient make a decision about eligibility. Main results No found which fulfilled all Two excluded because they did not any outcomes. Reviewer's conclusions After thorough search, no infections found. Therefore, at present time, there good quality evidence suggest it effective Well-designed parallel group, double blind comparing other versus placebo are needed. Outcomes should include reduction symptoms, sterilisation urine, side effects adherence therapy. Dosage (amount concentration) duration therapy assessed. Consumers clinicians will welcome these trials.

参考文章(18)
MILAP C. NAHATA, BRITT A. CUMMINS, DON C. McLEOD, RICHARD BUTLER, Predictability of methenamine efficacy based on type of urinary pathogen and pH. Journal of the American Geriatrics Society. ,vol. 29, pp. 236- 239 ,(1981) , 10.1111/J.1532-5415.1981.TB01774.X
J. Winberg, H. J. Andersen, T. Bergström, B. Jacobsson, H. Larson, K. Lincoln, EPIDEMIOLOGY OF SYMPTOMATIC URINARY TRACT INFECTION IN CHILDHOOD Acta Paediatrica. ,vol. 63, pp. 1- 20 ,(1974) , 10.1111/J.1651-2227.1974.TB05718.X
M. C. Nahata, B. A. Cummins, D. C. McLeod, S. W. Schondelmeyer, R. Butler, Effect of urinary acidifiers on formaldehyde concentration and efficacy with methenamine therapy. European Journal of Clinical Pharmacology. ,vol. 22, pp. 281- 284 ,(1982) , 10.1007/BF00545228
Anna Belle Kinney, Mary Blount, Effect of cranberry juice on urinary pH. Nursing Research. ,vol. 28, pp. 287- 290 ,(1979) , 10.1097/00006199-197909000-00012
D Zafriri, I Ofek, R Adar, M Pocino, N Sharon, Inhibitory activity of cranberry juice on adherence of type 1 and type P fimbriated Escherichia coli to eucaryotic cells. Antimicrobial Agents and Chemotherapy. ,vol. 33, pp. 92- 98 ,(1989) , 10.1128/AAC.33.1.92
EDWARD S. WONG, CYNTHIA L. FENNELL, WALTER E. STAMM, Urinary tract infection among women attending a clinic for sexually transmitted diseases. Sexually Transmitted Diseases. ,vol. 11, pp. 18- 23 ,(1984) , 10.1097/00007435-198401000-00004
A Hellstrom, E Hanson, S Hansson, K Hjalmas, U Jodal, Association between urinary symptoms at 7 years old and previous urinary tract infection. Archives of Disease in Childhood. ,vol. 66, pp. 232- 234 ,(1991) , 10.1136/ADC.66.2.232