Host-guest interaction of cucurbit[8]uril with oroxin A and its effect on the properties of oroxin A.
作者： Zhishu Zeng , Jun Xie , Guangyan Luo , Zhu Tao , Qianjun Zhang
DOI: 10.3762/BJOC.16.194
关键词: Nuclear chemistry 、 Infrared spectroscopy 、 Proton NMR 、 Chemistry 、 Inclusion compound 、 Antioxidant capacity 、 Solubility 、 Molar ratio 、 Binding constant
摘要: In this study, we investigated the host-guest interactions between oroxin A (OA) and cucurbit[8]uril (Q[8]) using 1H NMR, MS, UV-vis IR spectroscopy. The results showed that OA Q[8] formed an inclusion compound (OA@Q[8]) with a molar ratio of 1:1 binding constant 1.299 × 107 L·mol-1. addition, effect on properties was through comparative experiments. solubility in water increased 22.47-fold when concentration 1 10-4 mol·L-1. hardly affected antioxidant capacity OA, while cumulative release gastric juice 2.3-fold after forming Q[8].
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