HGF Increases Cisplatin Resistance via Down-Regulation of AIF in Lung Cancer Cells

作者: Jin-Tang Chen , Chih-Yang Huang , Yung-Yen Chiang , Wen-Heng Chen , Shiow-Her Chiou

DOI: 10.1165/RCMB.2007-0001OC

关键词: Focal adhesionImmunocytochemistryHepatocyte growth factorCancer researchGene expressionKinaseDownregulation and upregulationCell biologyCisplatinApoptosis-inducing factorBiologyClinical biochemistryMolecular biologyPulmonary and Respiratory Medicine

摘要: Our previous study had shown that advanced stages of lung adenocarcinomas (ADC) was frequently associated with overexpression of hepatocyte growth factor (HGF), which has …

参考文章(21)
Kuan-Chih Chow, Heng-Chien Ho, Liang-Shun Wang, Chih-Shiun Shih, Chun-Ming Tsai, Nan-Yung Hsu, Tze-Yi Lin, Overexpression of Dihydrodiol Dehydrogenase as a Prognostic Marker of Non-Small Cell Lung Cancer Cancer Research. ,vol. 61, pp. 2727- 2731 ,(2001)
Naoko Ishihara, Norio Takagi, Makiko Niimura, Keiko Takagi, Midori Nakano, Kouichi Tanonaka, Hiroshi Funakoshi, Kunio Matsumoto, Toshikazu Nakamura, Satoshi Takeo, Inhibition of apoptosis-inducing factor translocation is involved in protective effects of hepatocyte growth factor against excitotoxic cell death in cultured hippocampal neurons. Journal of Neurochemistry. ,vol. 95, pp. 1277- 1286 ,(2005) , 10.1111/J.1471-4159.2005.03446.X
Anna Janowska-Wieczorek, Peter Houghton, Janina Ratajczak, Marek Zembala, Stephen Peiper, Ela Trzyna, Mariusz Z. Ratajczak, John Trent, Ryan Reca, Kacper Jankowski, Marcin Wysoczynski, Magda Kucia, Dongling Zhao, Both Hepatocyte Growth Factor (HGF) and Stromal-Derived Factor-1 Regulate the Metastatic Behavior of Human Rhabdomyosarcoma Cells, But Only HGF Enhances Their Resistance to Radiochemotherapy Cancer Research. ,vol. 63, pp. 7926- 7935 ,(2003)
Seong-Woon Yu, Hongmin Wang, Marc F Poitras, Carmen Coombs, William J Bowers, Howard J Federoff, Guy G Poirier, Ted M Dawson, Valina L Dawson, Mediation of Poly(ADP-Ribose) Polymerase-1-Dependent Cell Death by Apoptosis-Inducing Factor Science. ,vol. 297, pp. 259- 263 ,(2002) , 10.1126/SCIENCE.1072221
Charles S. Smith, Vita M. Golubovskaya, Erin Peck, Li-Hui Xu, Brett P. Monia, Xihui Yang, William G. Cance, Effect of focal adhesion kinase (FAK) downregulation with FAK antisense oligonucleotides and 5-fluorouracil on the viability of melanoma cell lines. Melanoma Research. ,vol. 15, pp. 357- 362 ,(2005) , 10.1097/00008390-200510000-00003
Miguel-Angel Gallego, Bertrand Joseph, Therese H Hemström, Susan Tamiji, Laurent Mortier, Guido Kroemer, Pierre Formstecher, Boris Zhivotovsky, Philippe Marchetti, Apoptosis-inducing factor determines the chemoresistance of non-small-cell lung carcinomas. Oncogene. ,vol. 23, pp. 6282- 6291 ,(2004) , 10.1038/SJ.ONC.1207835
Kuan-Chih Chow, Shiow-Her Chiou, Shu-Peng Ho, Ming-Hsui Tsai, Chi-Long Chen, Liang-Shun Wang, Kwan-Hwa Chi, The elevated serum interleukin-6 correlates with the increased serum butyrate level in patients with nasopharyngeal carcinoma. Oncology Reports. ,vol. 10, pp. 813- 819 ,(2003) , 10.3892/OR.10.4.813
Jan Dörr, Karl Roth, Urte Zurbuchen, Rudolf Deisz, Ingo Bechmann, Thomas-Nicolas Lehmann, Susanne Meier, Robert Nitsch, Frauke Zipp, Tumor-necrosis-factor-related apoptosis-inducing-ligand (TRAIL)-mediated death of neurons in living human brain tissue is inhibited by flupirtine-maleate. Journal of Neuroimmunology. ,vol. 167, pp. 204- 209 ,(2005) , 10.1016/J.JNEUROIM.2005.06.027
P Stambolsky, L Weisz, I Shats, Y Klein, N Goldfinger, M Oren, V Rotter, Regulation of AIF expression by p53 Cell Death & Differentiation. ,vol. 13, pp. 2140- 2149 ,(2006) , 10.1038/SJ.CDD.4401965
ManLin Jin, Jennifer Yaung, Ram Kannan, Shikun He, Stephen J. Ryan, David R. Hinton, Hepatocyte growth factor protects RPE cells from apoptosis induced by glutathione depletion. Investigative Ophthalmology & Visual Science. ,vol. 46, pp. 4311- 4319 ,(2005) , 10.1167/IOVS.05-0353