作者: Nikolas Dovrolis , George Kolios , George Spyrou , Ioanna Maroulakou
DOI: 10.1016/J.DRUDIS.2017.03.009
关键词: Drug repositioning 、 Pipeline (software) 、 Ensemble analysis 、 Bioinformatics 、 In silico 、 Data science 、 Computer science
摘要: When faced with time- and money-consuming problems, new practices in pharmaceutical R&D arose when trying to alleviate them. Drug repositioning has great promise combined today's computational power intelligence it becomes more precise potent. This work showcases current approaches of creating a pipeline for drug repositioning, along an extensive example how researchers can influence therapeutic further understanding, through either single or multiple disease studies. paradigm is based on three neurodegenerative diseases pathophysiological similarities. It our goal provide the readers all information needed enrich their research note expectations way.