DOI: 10.1016/J.DRUDIS.2019.09.020
关键词: Biological materials 、 External source 、 Chemistry 、 Stem cell 、 Nanomedicine 、 Iron oxide nanoparticles 、 Cancer treatment 、 Nanotechnology 、 Advanced stage 、 Drug
摘要: In nanomedicine, iron oxide nanoparticles are at an advanced stage, being commercialized for cancer treatment and iron-deficiency anemia treatment. Their therapeutic efficacy comes from their ability to target a tissue, activate drug, locally produce temperature increase following (or not) the application of external source energy, modify genes or various biological materials, replace diseased cells by stem cells. Owing these mechanisms action, they can potentially be used treating whole range different diseases, making them more appealing than conventional drugs that limited number indications.