Prostate cancer promotes a vicious cycle of bone metastasis progression through inducing osteocytes to secrete GDF15 that stimulates prostate cancer growth and invasion.
作者： Wenchu Wang , Xin Yang , Jinlu Dai , Yi Lu , Jian Zhang
DOI: 10.1038/S41388-019-0736-3
关键词: Cell growth 、 Bone metastasis 、 Cancer research 、 Osteocyte 、 Cancer cell 、 Metastasis 、 Cell 、 Biology 、 Prostate cancer 、 Gene knockdown
摘要: Bone is the most frequent site of prostate cancer (PCa) metastasis; however, little is known about the role of the most common cell in bone, the osteocyte (OCy), in cancer biology. In this …
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