New evidence concerning mechanisms of action of vitamin E and selenium.

摘要: Publisher Summary This chapter examines the evidences concerning mechanisms of action vitamin E and selenium. Hypotheses selenium have been sharply divided between those holding that both these substances act simply as nonspecific biological antioxidants. It is found participates in activity glutathione peroxidase rat erythrocytes highly purified contains 4 gram atoms per mole enzyme. The levels livers selenium-deficient chicks also showed a severe drop, reaching very low by time were 13–15 clays age. drop occurred whether or not diet contained E. lipid peroxidation washed hepatic mitochondria microsomes from newly hatched breeding hens receiving was to be high. had little innate protection against peroxidation.