Artificial Pancreas Systems: An Introduction to the Special Issue

作者:

DOI: 10.1109/MCS.2017.2766321

关键词: MedicineAdipose tissueInternal medicineEndocrinologyGlycogenGlucagonInsulinArtificial pancreasType 1 diabetesDiabetes mellitusType 2 diabetes

摘要: People with diabetes cannot transfer the glucose in their bloodstream to various organs of body for consumption or storage later use. Blood concentration (BGC) increases by absorbing carbohydrates meals and converting them glucose. is consumed brain energy, stored liver (as glycogen) when BGC drops low levels a few hours after meal, transferred muscle fat cells utilization. The liver, muscle, adipose tissue can happen only if enabled insulin. Insulin produced secreted pancreas, which also produces glucagon digestive enzymes. Diabetes an autoimmune disease where producing insulin are compromised immune system. If most these (beta islets Langerhans pancreas) destroyed such that no produced, must be administered externally regulate BGC. Type 1 (T1D) refers people this state. In type 2 (T2D), some beta still functional, but total amount too used effectively. treatment options T2D include changes lifestyle, use medicine enhance productivity utilization efficiency, administration.

参考文章(4)
Aaron Kowalski, Pathway to Artificial Pancreas Systems Revisited: Moving Downstream Diabetes Care. ,vol. 38, pp. 1036- 1043 ,(2015) , 10.2337/DC15-0364
Aaron Kowalski, John W. Lum, Juvenile diabetes research foundation artificial pancreas consortium update. Journal of diabetes science and technology. ,vol. 3, pp. 1224- 1226 ,(2009) , 10.1177/193229680900300531
Ali Cinar, Multivariable Adaptive Artificial Pancreas System in Type 1 Diabetes. Current Diabetes Reports. ,vol. 17, pp. 88- ,(2017) , 10.1007/S11892-017-0920-1