Influence of Cyclooxygenase-2 Inhibitors on Kynurenic Acid Production in Rat Brain in Vitro
作者： Izabela Zakrocka , Katarzyna M. Targowska-Duda , Artur Wnorowski , Tomasz Kocki , Krzysztof Jóźwiak
DOI: 10.1007/S12640-018-9952-9
关键词: Pharmacology 、 Cyclooxygenase 、 Niflumic acid 、 Glutamatergic 、 Ionotropic effect 、 Central nervous system 、 Kynurenine 、 Glutamate receptor 、 Kynurenic acid 、 Chemistry
摘要: … of niflumic acid and parecoxib action in rat brain cortex independent from COX-2 inhibition. Through enzymatic inhibition of brain KYNA synthesis niflumic acid and parecoxib may be …
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