Evaluation of efficacy and tolerance of neuramide in the treatment of herpes zoster and postherpetic neuritis.

摘要: Ninety-two patients suffering from herpes zoster were enrolled in a double-blind controlled study aimed at evaluating the efficacy and tolerance of drug neuramide. Neuramide (N) placebo (P) administered to intramuscularly twice daily for 28 days as follows: group N + (patients always treated with neuramide); P neuramide 1 week, then placebo); placebo). During first all also standardized doses acyclovir. The presence extent clinical symptoms evaluated during 4 weeks, while appearance, degree duration postherpetic neuralgia both treatment over 6-month follow-up period. There no significant differences between four groups when subjective parameters (such pain paresis lesion site) examined. However, examination end showed that was therapeutic. Indeed, times recovery regeneration epithelium significantly shorter 3 weeks Furthermore, change vesicles crusts faster than group. Postherpetic neuritis occurred months follow-up. P, lasted throughout observation period, other this period shorter. there (p < 0.05) terms above complications following groups: P; N; P. No observed N, or groups. Taken together, these data demonstrate least reduces risk development.