Optimizing treatment approaches in seborrheic dermatitis.

作者: Goldenberg Gary

DOI:

关键词: DandruffDermatologyKeratolyticMedicineSebaceous glandErythemaSeborrheic dermatitisScalpDiseaseCutaneous condition

摘要: Seborrheic dermatitis is a chronic, recurring, cutaneous condition that causes erythema and flaking, sometimes appearing as macules or plaques with dry white moist oily scales. In adults, it commonly occurs in areas high concentrations of sebaceous glands. The face scalp are the most frequently affected areas, involvement multiple sites common. Dandruff regarded mild noninflammatory form seborrheic dermatitis. There incidence among persons human immunodeficiency virus infection Parkinson's disease. cause not well understood, but appears to be related composition gland secretions, proliferation Malessezia yeasts, host immune response. Treatment options for nonscalp include topical agents shampoos containing antifungal agents, anti-inflammatory keratolytic calcineurin inhibitors. Because body usually involved, physician should examine all areas. Patients made aware chronic will probably recur even after successful treatment.

参考文章(37)
William Abramovits, Joel Schlessinger, Boni E Elewski, Aditya K Gupta, Theodore Rosen, Sabra Abraham, Richard Rowell, Steven Kempers, A novel foam formulation of ketoconazole 2% for the treatment of seborrheic dermatitis on multiple body regions Journal of Drugs in Dermatology. ,vol. 6, pp. 1001- 1008 ,(2007)
I Stefanaki, A Katsambas, Therapeutic update on seborrheic dermatitis. Skin therapy letter. ,vol. 15, pp. 1- 4 ,(2010)
Boni Elewski, Tania J Phillips, Mark R Ling, Efficacy and safety of a new once-daily topical ketoconazole 2% gel in the treatment of seborrheic dermatitis: a phase III trial. Journal of Drugs in Dermatology. ,vol. 5, pp. 646- 650 ,(2006)
Wendy C Cantrell, Boni E Elewski, An open-label study of the safety and efficacy of sertaconazole nitrate in the treatment of seborrheic dermatitis. Journal of Drugs in Dermatology. ,vol. 10, pp. 895- ,(2011)
Grace K. Kim, Seborrheic Dermatitis and Malassezia species: How Are They Related? The Journal of clinical and aesthetic dermatology. ,vol. 2, pp. 14- 17 ,(2009)
J.-P. Ortonne, A.F. Nikkels, K. Reich, R.M. Ponce Olivera, J.H. Lee, N. Kerrouche, F. Sidou, J. Faergemann, Efficacious and safe management of moderate to severe scalp seborrhoeic dermatitis using clobetasol propionate shampoo 0·05% combined with ketoconazole shampoo 2%: a randomized, controlled study British Journal of Dermatology. ,vol. 165, pp. 171- 176 ,(2011) , 10.1111/J.1365-2133.2011.10269.X
R.J. Hay, Malassezia, dandruff and seborrhoeic dermatitis: an overview. British Journal of Dermatology. ,vol. 165, pp. 2- 8 ,(2011) , 10.1111/J.1365-2133.2011.10570.X
Jan Faergemann, Management of Seborrheic Dermatitis and Pityriasis Versicolor American Journal of Clinical Dermatology. ,vol. 1, pp. 75- 80 ,(2000) , 10.2165/00128071-200001020-00001
Thomas L. Dawson, Malassezia globosa and restricta: breakthrough understanding of the etiology and treatment of dandruff and seborrheic dermatitis through whole-genome analysis. The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research. ,vol. 12, pp. 15- 19 ,(2007) , 10.1038/SJ.JIDSYMP.5650049