Specific binding of human corticosteroid-binding globulin to cell membranes.

摘要: Abstract Specific binding sites for corticosteroid-binding globulin were detected on membranes prepared from human prostates. The are typical of membrane receptors: they saturable and specific have high affinity. There was little at 4 degrees C 23 C. Maximal obtained 37 Scatchard analysis revealed the presence a single set with an apparent dissociation constant 8.7 X 10(-7) M capacity 22 pmol/mg protein. globulin; not inhibited by testosterone/estradiol-binding globulin, albumin, or transferrin. density in several organs rhesus monkey is consistent hypothesis that involved transport steroid hormones into target tissues.