Electroanatomic Mapping of the Left Ventricle in a Porcine Model of Chronic Myocardial Infarction With Magnetic Resonance–Based Catheter Tracking

作者: Srinivas R. Dukkipati , Richard Mallozzi , Ehud J. Schmidt , Godtfred Holmvang , Andre d'Avila

DOI: 10.1161/CIRCULATIONAHA.107.738229

关键词: CatheterRadiologyCatheter ablationMagnetic resonance imagingVentricleIntracardiac injectionMedicineFluoroscopySubstrate mappingNuclear medicineMyocardial infarction

摘要: Background— X-ray fluoroscopy constitutes the fundamental imaging modality for catheter visualization during interventional electrophysiology procedures. The minimal tissue discriminative capability of is mitigated in part by use electroanatomic mapping systems and enhanced integration preacquired 3-dimensional heart with computed tomographic or magnetic resonance (MR) imaging. A more ideal paradigm might be to intraprocedural MR directly image guide Methods Results— An imaging–based system was designed assess feasibility navigating catheters left ventricle vivo using tracking microcoils incorporated into catheters, measuring intracardiac ventricular electrograms, integrating this information angiography myocardial delayed enhancement images allow substrate mapping. In all animals (4 normal, 10 chronically ...

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