Identification of two novel mammographic density loci at 6Q25.1
作者： Judith S Brand , Jingmei Li , Keith Humphreys , Robert Karlsson , Mikael Eriksson
DOI: 10.1186/S13058-015-0591-2
关键词: Genetics 、 Oncology 、 Breast cancer 、 Internal medicine 、 Polymorphism (computer science) 、 Genetic variation 、 Genetic association 、 MAMMOGRAPHIC DENSITY 、 Quantitative trait locus 、 Medicine 、 Genome-wide association study 、 Identification (biology)
摘要: Introduction Mammographic density (MD) is a strong heritable and intermediate phenotype for breast cancer, but much of its genetic variation remains unexplained. We performed large-scale association study including 8,419 women European ancestry to identify MD loci.
biomedcentral.com
springer.com
core.ac.uk
paperity.org参考文章(47)
Sarah Sherlock, Zhuang Liu, Qizhen Cao, Hongjie Dai, Xiaoyuan Chen, Corrine Davis, Kai Chen, Drug delivery with carbon nanotubes for in vivo cancer treatment arXiv: Materials Science. ,(2008) , 10.1158/0008-5472
Ralph Highnam, Sir Michael Brady, Martin J. Yaffe, Nico Karssemeijer, Jennifer Harvey, Robust breast composition measurement - Volpara™ international conference on digital mammography. pp. 342- 349 ,(2010) , 10.1007/978-3-642-13666-5_46
Pablo Fernandez-Navarro, Anna González-Neira, Guillermo Pita, Ramón Díaz-Uriarte, Leticia Tais Moreno, María Ederra, Carmen Pedraz-Pingarrón, Carmen Sánchez-Contador, Jose Antonio Vázquez-Carrete, Pilar Moreo, Carmen Vidal, Dolores Salas-Trejo, Jennifer Stone, Melissa C. Southey, John L. Hopper, Beatriz Pérez-Gómez, Javier Benitez, Marina Pollan, Genome wide association study identifies a novel putative mammographic density locus at 1q12-q21 International Journal of Cancer. ,vol. 136, pp. 2427- 2436 ,(2015) , 10.1002/IJC.29299
Jingmei Li, Laszlo Szekely, Louise Eriksson, Boel Heddson, Ann Sundbom, Kamila Czene, Per Hall, Keith Humphreys, High-throughput mammographic-density measurement: a tool for risk prediction of breast cancer Breast Cancer Research. ,vol. 14, pp. 1- 12 ,(2012) , 10.1186/BCR3238
J. S. Brand, K. Humphreys, D. J. Thompson, J. Li, M. Eriksson, P. Hall, K. Czene, Volumetric mammographic density: heritability and association with breast cancer susceptibility loci. Journal of the National Cancer Institute. ,vol. 106, ,(2014) , 10.1093/JNCI/DJU334
Giichi Takaesu, Satoshi Kishida, Atsushi Hiyama, Kyoko Yamaguchi, Hiroshi Shibuya, Kenji Irie, Jun Ninomiya-Tsuji, Kunihiro Matsumoto, TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway. Molecular Cell. ,vol. 5, pp. 649- 658 ,(2000) , 10.1016/S1097-2765(00)80244-0
Wei Zheng, Jirong Long, Yu-Tang Gao, Chun Li, Ying Zheng, Yong-Bin Xiang, Wanqing Wen, Shawn Levy, Sandra L Deming, Jonathan L Haines, Kai Gu, Alecia Malin Fair, Qiuyin Cai, Wei Lu, Xiao-Ou Shu, Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1 Nature Genetics. ,vol. 41, pp. 324- 328 ,(2009) , 10.1038/NG.318
S Cutrupi, S Reineri, A Panetto, E Grosso, L Caizzi, L Ricci, O Friard, S Agati, M Scatolini, G Chiorino, A E Lykkesfeldt, M De Bortoli, Targeting of the adaptor protein Tab2 as a novel approach to revert tamoxifen resistance in breast cancer cells Oncogene. ,vol. 31, pp. 4353- 4361 ,(2012) , 10.1038/ONC.2011.627
U Sovio, J Li, Z Aitken, K Humphreys, K Czene, S Moss, P Hall, V McCormack, I dos-Santos-Silva, Comparison of fully and semi-automated area-based methods for measuring mammographic density and predicting breast cancer risk. British Journal of Cancer. ,vol. 110, pp. 1908- 1916 ,(2014) , 10.1038/BJC.2014.82
Yanru Wang, Yisha He, Zhenzhen Qin, Yue Jiang, Guangfu Jin, Hongxia Ma, Juncheng Dai, Jiaping Chen, Zhibin Hu, Xiaoxiang Guan, Hongbing Shen, Evaluation of functional genetic variants at 6q25.1 and risk of breast cancer in a Chinese population Breast Cancer Research. ,vol. 16, pp. 422- 422 ,(2014) , 10.1186/S13058-014-0422-X