Mono and dinuclear bis(ortho-tolyl)platinum(II) compounds containing diethyl sulfide ligands: Synthesis, DFT studies and use as precursors in cycloplatination reactions
作者： Ramón Bosque , Margarita Crespo , Anna Escolà , Mercè Font-Bardia
DOI: 10.1016/J.JORGANCHEM.2017.11.020
关键词: Conformational isomerism 、 Monomer 、 Diethyl sulfide 、 Chemistry 、 Medicinal chemistry 、 Imine ligands 、 Denticity 、 Platinum 、 Dimer 、 Stereochemistry 、 Proton NMR
摘要: Abstract The synthesis of bis(ortho-tolyl)platinum(II) compounds containing diethyl sulfide ligands from [PtCl2(SEt2)2] and ortho-tolyl-lithium is presented. Formation a dimer [Pt(4-MeC6H4)2(μ-SEt2)]2 evidenced by 1H NMR HR-MS-ESI(+) spectra the monomer trans-anti-[Pt(2-MeC6H4)2(SEt2)2] characterized X-ray diffraction analyses. Theoretical studies indicate that dimerization most stable form (cis-syn) to conformer dinuclear species (αββα) favored (ΔE = −10.1 kJ/mol). reactions [Pt(4-MeC6H4)2(μ-SEt2)] with imine 4-ClC6H4CH = NCH2CH2NMe2 2-Br,6-FC6H3CH = NCH2Ph gave tridentate [C, N, N’] five-membered bidentate N] seven-membered platinacycles, respectively.
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