RNA editing by ADAR1 leads to context-dependent transcriptome-wide changes in RNA secondary structure
作者： Oz Solomon , Ayelet Di Segni , Karen Cesarkas , Hagit T. Porath , Victoria Marcu-Malina
DOI: 10.1038/S41467-017-01458-8
关键词: Cell biology 、 RNA editing 、 Nucleic acid secondary structure 、 Transcriptome 、 Nucleic acid 、 Post-transcriptional modification 、 Gene 、 Chemistry 、 Ribosomal RNA 、 RNA
摘要: Adenosine deaminase acting on RNA 1 (ADAR1) is the master RNA editor, catalyzing the deamination of adenosine to inosine. RNA editing is vital for preventing abnormal activation …
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