Energy provision, tissue utilization, and weight loss in prolonged starvation.

摘要: Daily weight loss measurements in 76 fasting, obese patients (58 females, 18 males) have shown a characteristic pattern of rapid initially (up to day 14) followed by slower but uniform reduction weight. There were significant sex differences. Measurements tissue breakdown showed that the initial was due continuing utilization nervous system glucose derived from lean tissue. This requirement fell noticeably second week starvation. Irreversible fluid elimination also contributed phase loss. Fat remained primary source energy throughout starvation and established fasting (more than 14 days) 96% requirement.