Aspects of neutron therapy based on an analysis of relationships between RBE and dose

作者: Tikvah Alper

DOI: 10.1259/0007-1285-45-529-39

关键词: MathematicsRadiation qualityDose per fractionEqual sizeRelative biological effectivenessNeutron therapyStatisticsFraction (mathematics)Fractionated irradiationNuclear medicine

摘要: The term “relative biological effectiveness” (RBE) is in almost universal use for comparing effects of radiations different quality. accepted definition (Storer et al., 1957), “Inverse the ratio doses to give same effect” might, perhaps, suggest that it a single valued parameter. However, now generally realized comparison quality given as RBE usually depends on level effect under consideration and state oxygenation irradiated material; also, some instances, dose-rate. When fractionated scheme used, size number dose fractions also affect RBE. It has been pointed out system per fraction when all treatment are equal (Fowler Morgan, 1963; Field, 1969). This true, course, only if any does not itself change nature response subsequent one. Comparing observations m...

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