Headspace single-drop microextraction for the analysis of chlorobenzenes in water samples.

摘要: Exposing a microlitre organic solvent drop to the headspace of an aqueous sample contaminated with ten chlorobenzene compounds proved be excellent preconcentration method for analysis by gas chromatography–mass spectrometry (GC–MS). The proposed single-drop microextraction (SDME) was initially optimised and optimum experimental conditions found were: 2.5l toluene microdrop exposed 5 min 10 ml containing 30% (w/v) NaCl placed in 15 vial stirred at 1000 rpm. calculated calibration curves gave high level linearity all target analytes correlation coefficients ranging between 0.9901 0.9971, except hexachlorobenzene where coefficient 0.9886. repeatability method, expressed as relative standard deviation varied 2.1 13.2% (n = 5). limits detection ranged 0.003 0.031g/l using GC–MS selective ion monitoring. Analysis spiked tap well water samples revealed that matrix had little effect on extraction. A comparative study performed solid-phase (SPME), extraction (SPE) EPA 8121. Overall, SDME rapid, simple sensitive technique chlorobenzenes samples, representing alternative traditional other, recently introduced, methods. © 2005 Elsevier B.V. All rights reserved.