Rapid preparative separation of monoclonal antibody charge variants using laterally-fed membrane chromatography.
作者： Rahul Sadavarte , Pedram Madadkar , Carlos DM Filipe , Raja Ghosh
DOI: 10.1016/J.JCHROMB.2017.12.003
关键词: Chemistry 、 Fragmentation (cell biology) 、 Column chromatography 、 Monoclonal antibody 、 Membrane 、 Antibody 、 Molecule 、 Isoelectric focusing 、 Chromatography 、 Immunoglobulin light chain
摘要: … As our next step, we attempted to scale-up the separation process developed with the 1 mL CEX LFMC device using a 4.96 mL LFMC device containing the same membrane. The flow …
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