Inclusion complexes with silybinin, their preparation and pharmaceutical compositions containing them

作者: Wilfried Peter Dr. Rer. Nat. Wachter , Jozsef Prof. Dr. Szejtli , Umberto Prof. Valcavi , Roberto Dr. Caponi , Enrico Dr. Bosone

DOI:

关键词: BioavailabilityCyclodextrinChromatographyChemistryCombinatorial chemistryDerivative (chemistry)

摘要: The invention relates to inclusion complexes of Silybinin with a cyclodextrin selected from the group consisting α-, β- and γ-cyclodextrin suitable derivative thereof method for preparation thereof. showed highly improved bioavailability in comparison which makes them particularly interesting treatment various hepatotoxic conditions.

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