Protective effect of bicyclol against bile duct ligation-induced hepatic fibrosis in rats

作者: Yong-Zhan Zhen , Na-Ren Li , Hong-Wei He , Shuang-Shuang Zhao , Guang-Ling Zhang

DOI: 10.3748/WJG.V21.I23.7155

关键词: DrugBiologyPathologyBile duct ligationHepatic fibrosisLiver fibrosisCholestatic liver diseaseGene expression

摘要: CONCLUSION: Bicyclol significantly attenuates BDL-induced liver fibrosis by reversing fibrogenic gene expression. These findings suggest that bicyclol might be an effective anti-fibrotic drug for the treatment of cholestatic disease.

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