Schizophrenia, Psychopharmacology, and Pregnancy

摘要: Most women with schizophrenia have children at some point in their lives despite reduced fertility compared the general population. They often stop psychotropic medication due to concerns about harming infant and it is not clear what extent they are risk of relapse pregnancy, though there good evidence that postpartum period a time increased risk. Their pregnancies adverse outcomes including pre-eclampsia, poor fetal growth, preterm birth, low birth weight, still births, neonatal post-neonatal deaths. Lifestyle factors, such as smoking nutritional deficiencies, likely explain many these outcomes. Current suggests most antipsychotics unlikely be major teratogens, unclear other outcomes, developmental related or confounders. Pregnancy diagnosis should considered high managed accordingly. A focus on reducing modifiable obesity smoking, ideally before conception, well optimising antenatal care using lowest effective doses appropriate monitoring through key improving long-term vulnerable families.