The inhibition of the fatty acid oxygenase of sheep vesicular gland by antioxidants
作者： Jack Y. Vanderhoek , William E.M. Lands
DOI: 10.1016/0005-2760(73)90096-9
关键词: Biochemistry 、 Lipoxygenase 、 Enzyme 、 Oxygenase 、 Inhibitory postsynaptic potential 、 Chemistry 、 Fatty acid 、 Substrate analog 、 Antioxidant 、 Biophysics 、 Endocrinology
摘要: Abstract Antioxidants inhibit the fatty acid oxygenase of sheep vesicular gland and soybean lipoxygenase in an instantaneous, reversible manner. Their inhibitory effectiveness was not related to their traditional antioxidant potencies but seemed depend on nature enzyme. The destructive effect ofeicosa-5,8,11,14-tetraynoic acid, a substrate analog, could be prevented presence either α-naphthol or 2,2,4-trimethyl-6-ethoxy-1,2-dihydroquinoline (Santoquin).
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