The implication of mitochondrial dysfunction and mitochondrial oxidative damage in di (2-ethylhexyl) phthalate induced nephrotoxicity in both in vivo and in vitro models

作者: Sorour Ashari , Mohammad Karami , Mohammad Shokrzadeh , Morteza Ghandadi , Nasrin Ghassemi-Barghi

DOI: 10.1080/15376516.2020.1758980

关键词: PhthalateNephrotoxicityMitochondrionIn vivoPharmacologyPhthalic acidOxidative stressMetaboliteChemistryIn vitro

摘要: Di-(2-ethylhexyl) phthalate (DEHP) and its main metabolite, monoethylhexyl phthalic acid (MEHP), are a serious threat to human animals’ health in the current century. However, their exact mecha...

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