Drug dependence: stress and dysregulation of brain reward pathways.

作者: Mary Jeanne Kreek , George F. Koob

DOI: 10.1016/S0376-8716(98)00064-7

关键词: NeuroplasticityAddictionClinical researchClinical psychologyDevelopmental psychologyReinforcementBrain stimulation rewardAnxietyPsychologyDysphoriaDrug

摘要: Examines the hypothesis that negative affective states can contribute to the reinforcement associated with drug taking by changing the set point for hedonic processing or the set point …

参考文章(227)
Barbara J. Mason, Eva C. Ritvo, Robert O. Morgan, Femando R. Salvato, Gloria Goldberg, Bruce Welch, Emilio Mantero-Atienza, A Double‐Blind, Placebo‐Controlled Pilot Study to Evaluate the Efficacy and Safety of Oral Nalmefene HCI for Alcohol Dependence Alcoholism: Clinical and Experimental Research. ,vol. 18, pp. 1162- 1167 ,(1994) , 10.1111/J.1530-0277.1994.TB00098.X
Michael J. Kuhar, Nancy S. Pilotte, Neurochemical changes in cocaine withdrawal. Trends in Pharmacological Sciences. ,vol. 17, pp. 260- 264 ,(1996) , 10.1016/0165-6147(96)10024-9
Zoltán Sarnyai, Éva Bíró, János Gardi, Miklós Vecsernyés, János Julesz, Gyula Telegdy, Alterations of corticotropin-releasing factor-like immunoreactivity in different brain regions after acute cocaine administration in rats Brain Research. ,vol. 616, pp. 315- 319 ,(1993) , 10.1016/0006-8993(93)90224-B
C. O'Brien, T Testa, T. O'Brien, J. Brady, B Wells, Conditioned narcotic withdrawal in humans Science. ,vol. 195, pp. 1000- 1002 ,(1977) , 10.1126/SCIENCE.841320
F. E. Pontieri, G. Tanda, G. Di Chiara, Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 92, pp. 12304- 12308 ,(1995) , 10.1073/PNAS.92.26.12304
W.K.K. Ho, H.L. Wen, K.P. Fung, Y.H. Ng, K.K. Au, L. Ma, Comparison of plasma hormonal levels between heroin-addicted and normal subjects. Clinica Chimica Acta. ,vol. 75, pp. 415- 419 ,(1977) , 10.1016/0009-8981(77)90360-6
Nancy K Mello, Jack H Mendelson, Cocaine’s Effects on Neuroendocrine Systems: Clinical and Preclinical Studies Pharmacology Biochemistry and Behavior. ,vol. 57, pp. 571- 599 ,(1997) , 10.1016/S0091-3057(96)00433-9