[5,4-d] pyrimidine on the circulation of experimental myocardial infarct and healthy myocardium].
作者： Manfred Kiese , Gerhard Lange , Klaus Resag
DOI: 10.1007/BF02045659
关键词: Internal medicine 、 Pyrimidine 、 Myocardial infarction 、 Vasodilator agents 、 Cardiology 、 Medicine
摘要: 2,6-Bis (diathanolamino)-4,8-dipiperidino-pyrimido (5,4-d) pyrimidin (RA 8,Persantin) bewirkte bei narkotisierten Hunden nach intravenoser Injektion von 0,03–2 mg/kg Vermehrung der Durchblutung des Herzmuskels. Dosen 0,3–0,4 mg RA 8/kg waren ebenso stark wirksam wie 5 Theophyllin/kg.
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sci-hub.se 参考文章(7)
Kadatz R, [Pharmacological properties of a new coronary dilator substance 2, 6-bis(diethanolamino)-4, 8-dipiperidino-pyrimido[5,4-d]pyrimidine]. Drug Research. ,vol. 9, pp. 39- 45 ,(1959)
Donald Dexter Van Slyke, John Punnett Peters, Quantitative clinical chemistry Williams & Wilkins. ,(1931)
E. H. Starling, M. B. Visscher, The regulation of the energy output of the heart The Journal of Physiology. ,vol. 62, pp. 243- 261 ,(1927) , 10.1113/JPHYSIOL.1927.SP002355
G. Lange, Messung der Durchblutung im Herzinfarkt Naunyn-schmiedebergs Archives of Pharmacology. ,vol. 236, pp. 225- 225 ,(1959) , 10.1007/BF00259137
Grabner G, Kaindl F, Kraupp O, [Effects of 2, 6-bis(diethanolamino)-4, 8-dipiperidino-pyrimido[5, 4-d]pyrimidine on cardiac activity and coronary circulation in anesthetized dogs]. Drug Research. ,vol. 9, pp. 45- ,(1959)
Frank A, Bernard U, Scheler F, Kochsiek K, Bretschneider Hj, [Effect of a pyrimido-pyrimidine derivative on the oxygen supply of the heart muscle]. Drug Research. ,vol. 9, pp. 49- 59 ,(1959)
Bogelmann G, Hockerts T, [Studies on the effect of 2, 6-bis(diethanolamino)-4, 8-dipiperidino-pyrimido[5, 4-d]-pyrimidine on the heart and circulation]. Drug Research. ,vol. 9, pp. 47- ,(1959)