作者: Carlo Agostoni , Giovanni Fattore
DOI: 10.1159/000342527
关键词: Population 、 Compensatory growth (organism) 、 Gerontology 、 Child development 、 Environmental health 、 Medicine 、 Quality-adjusted life year 、 Psychological intervention 、 Breast feeding 、 Malnutrition 、 Nutrition Disorders
摘要: Increasing evidence points to a fundamental role of early nutrition on rates growth and development, later health. We may identify three major fields scientific interest clinical application. (1) In developing countries poor is associated with greater risk morbidity mortality from infectious diseases, mainly lower respiratory infections diarrhea. these settings, failure promote compensatory have negative short-term consequences, the nutritionist's task primary prevention nutrient deficiencies full expression individual genetic potential, while allowing for recovery secondary functional deficiencies. (2) A second challenge nutritionists represented by approach impairments in rare disorders, ranging congenital disorders chronic infections. Most are favorably influenced improved nutritional status better growth, patients satisfactorily reach adolescence, pubertal reproductive age, up ageing. Even less positive conditions, an improvement quality life families any case rewarding aim. (3) third definition physiological conditions all individuals. Concern has been raised about potential adverse long-term consequences accelerated child rates, possibly resulting predisposition develop non-communicable diseases adult age. Accordingly, this hypothesis might explain benefits breastfeeding terms slower fetal origins postnatal catch-up infants born small. Therefore, as viewed pediatric nutritionist perspective complex matter, stages intrauterine development ages ageing processes. Cost/benefit analyses interventions such cost per DALYs (disability-adjusted years) or QALYs (quality-adjusted should be expanded population basis extended also invalidating most effective economic sustainable strategies action.