Methods for enriching fetal cells from maternal body fluids

摘要: The present invention relates to methods of enriching fetal cells from maternal body fluids. In particular, it the use a cell-trap centrifugation tube containing gradient solution adjusted specific density enrich for nucleated red blood blood. allows desired cell population be collected by decantation after minimize loss and maximize efficiency. addition, method can further simplified density-adjusted sorting which uses type-specific binding agents such as antibodies lectins linked carrier particles impart different undesired populations allowing separated during in more convenient manner. rapid enrichment described herein has wide range applications, including but not limited to, gender determination prenatal diagnosis genetic diseases without invasive procedures.