Mechanism and regulation of transcriptional elongation by RNA polymerase II.

作者: Daniel Reines , Ronald C Conaway , Joan Weliky Conaway

DOI: 10.1016/S0955-0674(99)80047-7

关键词: ElongationTranscription (biology)Elongation factorBiologyGeneticsTranscription factorRegulation of gene expressionRNA polymerase IICell biologyDNA repairTranscription factor II D

摘要: Over the past few years, biochemical and genetic studies have shed considerable light on structure function of RNA polymerase II (pol II) elongation complex transcription factors that control it. Novel been identified their mechanisms action characterized in increasing detail; new insights into biological roles gained from regulation mRNA synthesis yeast; intriguing links between pol machinery pathways DNA repair recombination emerged.

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