Maintenance of gene expression patterns.
作者： Hugh W. Brock , Cynthia L. Fisher
DOI: 10.1002/DVDY.20298
关键词: DNA-binding protein 、 Epigenetics 、 Transcription factor 、 Trithorax-group proteins 、 Genetics 、 Histone methylation 、 Biology 、 Gene expression 、 Gene silencing 、 Cell division 、 Cell biology
摘要: In development, cells pass on established gene expression patterns to daughter over multiple rounds of cell division. The cellular memory the state is termed maintenance, and proteins required for this process are maintenance proteins. best characterized Polycomb trithorax Groups that silencing activation target loci, respectively. These act through DNA elements elements. Here, we re-examine genetics molecular biology We discuss models silencing, establishment epigenetic marks, suggest may play a role in propagating mark synthesis.
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