Results of One-Stage or Staged Amputations of Lower Limbs Consequent to Critical Limb Ischemia and Infection

摘要: Background Amputations of lower limbs can be conducted as one-stage amputation (OSA) or staged (SA) procedures. The objective this study was to analyze technical success and mortality rates both techniques, well factors that might influence outcomes in patients with critical limb ischemia (CLI). Methods A retrospective 185 consecutive CLI who underwent amputations the period 2004–2011. Primary end points were (healing without dehiscence reintervention) mortality. on demographic data, clinical status, comorbidities also analyzed by logistic regression. Results total 101 SA (91 patients) 106 OSA (94 analyzed. had proportionally higher rate (SA 77.2% vs. 66.0%, P  = 0.0253), perioperative (SA, 10.9% OSA, 20.7%,  = 0.0247), 30-day 12.2% 23.8%,  = 0.0220) spite more cases Rutherford classes 5 6 87.1% 72.6%,  = 0.0047), diabetes (71.2% 55.6%,  = 0.0076), infection (44.5% 28.3%,  = 0.0061). Logistic regression demonstrated SA, frequent did not use insulin (  = 0.0072), those transfemoral  = 0.0392), no coronary artery disease  = 0.0053), foot  = 0.0446), while for nondiabetic  = 0.0077),  = 0.0298), at level  = 0.0155),  = 0.0030). Conclusions a than even greater number severe infection. However, prospective studies comparing techniques are needed further evidence.