The crystal structure of phosphorylase b at 6 Å resolution
作者： L.N. Johnson , N.B. Madsen , J. Mosley , K.S. Wilson
DOI: 10.1016/0022-2836(74)90534-8
关键词: Chemistry 、 Crystal structure 、 Substrate (chemistry) 、 Dimer 、 Electron density 、 Symmetry (physics) 、 Resolution (electron density) 、 Crystallography 、 Binding site 、 Molecule
摘要: Abstract The determination of the crystal structure phosphorylase b in presence IMP at 6 A resolution is described. based on two heavy-atom isomorphous derivatives and their anomalous contributions. molecular boundary clearly distinguishable electron density map, except region subunit-subunit contact about crystallographic dyad axis, which symmetry axis dimer. dimer molecule roughly ellipsoidal shape with dimensions 63 × 116 A. There a pronounced cavity enzyme surface but it not yet known if this substrate binding site.
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